Middleweight champion Dricus du Plessis makes his third title defense Saturday against challenger Khamzat Chimaev in the main event of UFC 319. The main card is set for 10 p.m. ET from the United Center in Chicago.

Chimaev is a -250 favorite (risk $250 to win $100), while du Plessis fetches a price of +205 (risk $100 to win $205) in the latest MMA odds for UFC 319: du Plessis vs. Chimaev. 

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Before making any UFC 319 picks, make sure you see the MMA predictions and betting advice from SportsLine expert Daniel Vithlani. 

Vithlani is a highly analytical UFC bettor who has been a consistent winner for SportsLine members since making his debut in January 2023 with a 5-0 record for UFC 283. In fact, he’s up over $1,500 on his UFC main card picks!

His other highlights include calling an upset for Sean O’Malley (+210) against Aljamain Sterling (-250) at UFC 292 as part of a 4-1 main card, and his UFC 299 winners included underdog selections on Dustin Poirier (+190) against Benoit Saint Denis (-230) and Michael Page (+110) against Kevin Holland (-130). Anyone who has followed him could be way up.

This week at UFC 319: du Plessis vs. Chimaev, we can tell you Vithlani is backing Chase Hooper (-295) to get past Alexander Hernandez (+240) in a lightweight matchup on the preliminary card. 

He’s also backing a fighter who “is a dynamic fighter with some incredible highlight finishes” to pull off a MASSIVE victory! You ABSOLUTELY need to see his UFC Fight Night picks before making any of your own!

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